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1

Imatinib as the first-line treatment of patients with chronic myeloid leukemia diagnosed in the chronic phase: Can we compare real life data to the results from clinical trials?

Daniela Zackova, Hana Klamova, Ladislav Dusek, Jan Muzik, Katerina Machova Polakova, Jana Moravcova, Tomas Jurcek, Dana Dvorakova, Zdenek Racil, Zdenek Pospisil, Alexandra Oltova, Kyra Michalova, Jana

Journal:

American Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

2

Persistent splenomegaly during imatinib therapy and the definition of complete hematological response in chronic myelogenous leukemia

Zdenek Racil, Hana Klamova, Jaroslava Voglova, Edgar Faber, Filip Razga, Daniela Zackova, Lucie Buresova, Petr Cetkovsky, Jiri Mayer

Journal:

American Journal of Hematology

Year:

2010

Language:

english

File:

PDF, 1.23 MB

english, 2010

3

Differences and similarities in kinetics of BCR-ABL transcript levels in CML patients treated with imatinib mesylate for chronic or accelerated disease phase

Jana Moravcová, Václava Zmeková, Hana Klamová, Jaroslava Voglová, Edgar Faber, Kyra Michalová, Jana Rabasová, Marie Jarošová

Journal:

Leukemia Research

Year:

2004

Language:

english

File:

PDF, 65 KB

english, 2004

4

CML patient with rare b2a3 (e13a3) variant of BCR–ABL transcript: Complete molecular response to imatinib

Jana Moravcová, Jana Rulcová, Jaroslav Polák, Zuzana Zemanová, Hana Klamová, Cedrik Haškovec

Journal:

Leukemia Research

Year:

2005

Language:

english

File:

PDF, 65 KB

english, 2005

5

Gene expression profiles of two accelerations in a CML patient

Karel Fišer, Hana Klamová, Jana Moravcová

Journal:

Leukemia Research

Year:

2006

Language:

english

File:

PDF, 314 KB

english, 2006

6

The effect of total-ABL, GUS and B2M control genes on BCR-ABL monitoring by real-time RT-PCR

Jana Rulcová, Václava Zmeková, Zuzana Zemanová, Hana Klamová, Jana Moravcová

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 462 KB

english, 2007

7

High-resolution melt curve analysis: Initial screening for mutations in BCR-ABL kinase domain

Kateřina Machová Poláková, Tereza Lopotová, Hana Klamová, Jana Moravcová

Journal:

Leukemia Research

Year:

2008

Language:

english

File:

PDF, 787 KB

english, 2008

8

Control genes in international standardization of real-time RT-PCR for BCR-ABL

Jana Moravcová, Jana Rulcová, Kateřina Machová Poláková, Hana Klamová

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 141 KB

english, 2009

9

Response to treatment in women with chronic myeloid leukemia during pregnancy and after delivery

Hana Klamová, Markéta Marková, Jana Moravcová, Magda Šišková, Petr Cetkovský, Kateřina Machová Poláková

Journal:

Leukemia Research

Year:

2009

Language:

english

File:

PDF, 106 KB

english, 2009

10

Effect of the duration and quality of peripheral blood sample storage on the results of qualitative and quantitative BCR-ABL transcript analyses in patients with CML

Jana Moravcová, Jana Rulcová-Karavdić, Adéla Broučková, Hana Klamová

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 197 KB

english, 2011

11

MicroRNA-451 in chronic myeloid leukemia: miR-451–BCR-ABL regulatory loop?

Tereza Lopotová, Markéta Žáčková, Hana Klamová, Jana Moravcová

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 406 KB

english, 2011

12

The reactivity of monoclonal antibodies against cytokine receptors with different lymphoid and myeloid leukemic cells

K. Koubek, J. Starý, A. Jirásek, H. Klamová, P. Skopový, O. Babušíková

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 157 KB

english, 1997

13

Selective destruction of leukaemic cells by photo-activation of 5-aminolaevulinic acid-induced protoporphyrin-IX

Dana Grebeňová, Hana Cajthamlová, Jitka Bartošová, Juri Marinov, Hana Klamová, Ota Fuchs, Zbyněk Hrkal

Journal:

Journal of Photochemistry and Photobiology B: Biology

Year:

1998

Language:

english

File:

PDF, 1.04 MB

english, 1998

14

P230 BCR/ABL protein may be associated with an acute leukaemia phenotype

Cedrik Haškovec, Carola Ponzetto, Jaroslav Polák, Diego Maritano, Zuzana Zemanová, Anna Serra, Kyra Michalová, Hana Klamová, JARoslav Čermák, Giuseppe Saglio

Journal:

British Journal of Haematology

Year:

1998

Language:

english

File:

PDF, 179 KB

english, 1998

15

Estimation of current cumulative incidence of leukaemia-free patients and current leukaemia-free survival in chronic myeloid leukaemia in the era of modern pharmacotherapy

Tomáš Pavlík, Eva Janoušová, Zdeněk Pospíšil, Jan Mužík, Daniela Žáčková, Zdeněk Ráčil, Hana Klamová, Petr Cetkovský, Marek Trněný, Jiří Mayer, Ladislav Dušek

Journal:

BMC Medical Research Methodology

Year:

2011

Language:

english

File:

PDF, 348 KB

english, 2011

16

Expression patterns of microRNAs associated with CML phases and their disease related targets

Kateřina Machová Poláková, Tereza Lopotová, Hana Klamová, Pavel Burda, Marek Trněný, Tomáš Stopka, Jana Moravcová

Journal:

Molecular Cancer

Year:

2011

Language:

english

File:

PDF, 2.50 MB

english, 2011

17

To the intranucleolar translocation of AgNORs in leukemic early granulocytic and plasmacytic precursors

Karel Smetana, Hana Klamová, Michaela Pluskalová, Petr Stöckbauer, Zbyněk Hrkal

Journal:

Histochemistry and Cell Biology

Year:

2006

Language:

english

File:

PDF, 346 KB

english, 2006

18

Targeting of gene expression by siRNA in CML primary cells

Michaela Merkerova, Hana Klamova, Radim Brdicka, Hana Bruchova

Journal:

Molecular Biology Reports

Year:

2007

Language:

english

File:

PDF, 261 KB

english, 2007

19

The predictive value ofhuman organic cation transporter 1andABCB1expression levels in different cell populations of patients with de novo chronic myelogenous leukemia

Filip Razga, Zdenek Racil, Katerina Machova Polakova, Lucie Buresova, Hana Klamova, Daniela Zackova, Dana Dvorakova, Vaclava Polivkova, Petr Cetkovsky, Jiri Mayer

Journal:

International Journal of Hematology

Year:

2011

Language:

english

File:

PDF, 1.55 MB

english, 2011

20

Late molecular relapse in two CML patients in molecular remission after donor lymphocyte transfusion for post-BMT relapse

Moravcová, J, Muchová, S, Lukášová, M, Klamová, H, Březinová, J, Gašová, Z

Journal:

Bone Marrow Transplantation

Year:

1999

Language:

english

File:

PDF, 39 KB

english, 1999

21

A new case of chronic myeloid leukemia (CML) in myeloid blast crisis with an atypical (b3/a3) junction of the BCR/ABL gene

Polák, J, Zemanová, Z, Michalová, K, Klamová, H, Čermák, J, Haškovec, C

Journal:

Year:

1998

Language:

english

File:

PDF, 23 KB

english, 1998

22

Nucleolar and cytoplasmic RNA density–concentration in leukemia granulocytic progenitors in human bone marrow biopsies: A short cytochemical note

Karel Smetana, Ilona Jirásková, Dana Mikulenková, Hana Klamová

Journal:

Acta Histochemica

Year:

2011

Language:

english

File:

PDF, 450 KB

english, 2011

23

A short cytochemical note on the nucleolar and cytoplasmic RNA concentration in differentiating cells represented by human erythroblasts

K. Smetana, H. Klamová, I. Jirásková, D. Mikulenková

Journal:

Acta Histochemica

Year:

2010

Language:

english

File:

PDF, 283 KB

english, 2010

24

Complex chromosomal rearrangements in patients with chronic myeloid leukemia

Libuse Babicka, Zuzana Zemanova, Lenka Pavlistova, Jana Brezinova, Sarka Ransdorfova, Lucie Houskova, Jana Moravcova, Hana Klamova, Kyra Michalova

Journal:

Cancer Genetics and Cytogenetics

Year:

2006

Language:

english

File:

PDF, 329 KB

english, 2006

25

Constant BCR-ABL transcript level ≥0.1% (IS) in patients with CML responding to imatinib with complete cytogenetic remission may indicate mutation analysis

Kateřina Machová Poláková, Václava Polívková, Jana Rulcová, Hana Klamová, Tomáš Jurček, Dana Dvořáková, Daniela Žáčková, Zdeněk Pospíšil, Jiří Mayer, Jana Moravcová

Journal:

Experimental Hematology

Year:

2010

Language:

english

File:

PDF, 282 KB

english, 2010

26

N-terminally truncated WT1 variant (sWT1) is expressed at very low levels in acute myeloid leukemia and advanced phases of chronic myeloid leukemia

Tereza Lopotová, Sylvie Nádvorníková, Markéta Žáčková, Jaroslav Polák, Jiří Schwarz, Hana Klamová, Jana Moravcová

Journal:

Leukemia Research

Year:

2012

Language:

english

File:

PDF, 318 KB

english, 2012

27

Occurrence of cytokine receptors on different lymphoid leukaemic cells

Kristian Koubek, Jan Starý, Andrea Kumberová, Hana Klamová, Martin Filipec

Journal:

European Journal of Haematology

Year:

1999

Language:

english

File:

PDF, 800 KB

english, 1999

28

Are microproerythroblasts in human bone marrow real or artefacts? A cytochemical note

Karel Smetana, Ilona Jirásková, Hana Klamová

Journal:

Acta Histochemica

Year:

2005

Language:

english

File:

PDF, 676 KB

english, 2005

29

CEBPA polymorphisms and mutations in patients with acute myeloid leukemia, myelodysplastic syndrome, multiple myeloma and non-Hodgkin's lymphoma

Ota Fuchs, Dana Provaznikova, Marcela Kocova, Arnost Kostecka, Pavla Cvekova, Radana Neuwirtova, Petr Kobylka, Jaroslav Cermak, Jana Brezinova, Jiri Schwarz, Jana Markova, Peter Salaj, Hana Klamova, J

Journal:

Blood Cells, Molecules, and Diseases

Year:

2008

Language:

english

File:

PDF, 437 KB

english, 2008

30

Expression of four major WT1 splicing variants in acute and chronic myeloid leukemia patients analyzed by newly developed four real-time RT PCRs

Tereza Lopotová, Jaroslav Polák, Jiří Schwarz, Hana Klamová, Jana Moravcová

Journal:

Blood Cells, Molecules, and Diseases

Year:

2012

Language:

english

File:

PDF, 877 KB

english, 2012

31

The nucleolar functional asynchrony — imbalance — in the granulopoietic proliferating compartment of patients suffering from chronic myeloid leukemia

Karel Smetana, Hana Klamová, Ilona Jirásková, Hana Šubrtová, Ladislav Rosa

Journal:

Year:

1998

Language:

english

File:

PDF, 433 KB

english, 1998

32

Hsp90 — a potential prognostic marker in CML

Žáčková, Markéta, Moučková, Darina, Lopotová, Tereza, Ondráčková, Zuzana, Klamová, Hana, Moravcová, Jana

Journal:

Blood Cells, Molecules, and Diseases

Year:

2013

Language:

english

File:

PDF, 624 KB

english, 2013

33

Gene Expression Profiling in Chronic Myeloid Leukemia Patients Treated with Hydroxyurea

Bruchova, Hana, Borovanova, Tereza, Klamova, Hana, Brdicka, Radim

Journal:

Leukemia and Lymphoma

Year:

2002

Language:

english

File:

PDF, 6.69 MB

english, 2002

34

Efficacy and tolerance of dasatinib after imatinib failure or intolerance for patients with chronic myeloid leukemia treated in three different hospitals compare well with results achievable in formal clinical trials

Zackova, Daniela, Klamova, Hana, Muzik, Jan, Cmunt, Eduard, Racil, Zdenek, Machova Polakova, Katerina, Dvorakova, Dana, Jurcek, Tomas, Razga, Filip, Cetkovsky, Petr, Dusek, Ladislav, Mayer, Jiri

Journal:

Leukemia and Lymphoma

Year:

2013

Language:

english

File:

PDF, 217 KB

english, 2013

35

No clinical evidence for performing trough plasma and intracellular imatinib concentrations monitoring in patients with chronic myelogenous leukaemia

Racil, Zdenek, Razga, Filip, Klamova, Hana, Voglova, Jaroslava, Belohlavkova, Petra, Malaskova, Ludmila, Potesil, David, Muzik, Jan, Zackova, Daniela, Polakova, Katerina Machova, Zdrahal, Zbynek, Mala

Journal:

Hematological Oncology

Year:

2014

Language:

english

File:

PDF, 308 KB

english, 2014

36

The DNA chromatin condensation expressed by the image optical density of chromosomes and heterochromatin in proliferating single human leukemic granulocytic progenitors

Smetana, Karel, Klamová, Hana, Jirásková, Ilona, Mikulenková, Dana, Zápotocký, Michal, Hrkal, Zbynèk

Journal:

Journal of Applied Biomedicine

Year:

2012

Language:

english

File:

PDF, 1.42 MB

english, 2012

37

The heterochromatin condensation state in central nuclear regions of individual granulocytes

Smetana, Karel, Mikulenková, Dana, Klamová, Hana

Journal:

Journal of Applied Biomedicine

Year:

2013

Language:

english

File:

PDF, 540 KB

english, 2013

38

Corrigendum to “Expression of four major WT1 splicing variants in acute and chronic myeloid leukemia patients analyzed by newly developed four real-time RT PCRs” [Blood Cells Mol. Dis. 49 (1) (2012) 41–47]

Lopotová, Tereza, Polák, Jaroslav, Schwarz, Jiří, Klamová, Hana, Moravcová, Jana

Journal:

Blood Cells, Molecules, and Diseases

Year:

2013

Language:

english

File:

PDF, 98 KB

english, 2013

39

BCR-ABL mutations in chronic myeloid leukemia–Not only detection

Polakova, Katerina Machova, Zmekova, Vaclava, Rulcova, Jana, Klamova, Hana, Zemanova, Zuzana, Moravcova, Jana

Journal:

Leukemia and Lymphoma

Year:

2008

Language:

english

File:

PDF, 251 KB

english, 2008

40

Expression of cyclins D1, D2 and D3 and Ki-67 in human leukemia

Jaroslav, Polák, Martina, Hradcová, Jiří, Schwarz, Hana, Klamová, Petr, Stöckbauer, Tomáš, Kozák, Julius, Müller, Cedrik, Haškovec

Journal:

Leukemia and Lymphoma

Year:

2005

Language:

english

File:

PDF, 302 KB

english, 2005

41

Next-generation deep sequencing improves detection ofBCR-ABL1kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase

Machova Polakova, Katerina, Kulvait, Vojtech, Benesova, Adela, Linhartova, Jana, Klamova, Hana, Jaruskova, Monika, de Benedittis, Caterina, Haferlach, Torsten, Baccarani, Michele, Martinelli, Giovanni

Journal:

Journal of Cancer Research and Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 1.62 MB

english, 2015

42

Current survival measures reliably reflect modern sequential treatment in CML: Correlation with prognostic stratifications

Pavlik, Tomas, Janousova, Eva, Mayer, Jiri, Indrak, Karel, Jarosova, Marie, Klamova, Hana, Zackova, Daniela, Voglova, Jaroslava, Faber, Edgar, Karas, Michal, Machova Polakova, Katerina, Racil, Zdenek,

Journal:

American Journal of Hematology

Year:

2013

Language:

english

File:

PDF, 176 KB

english, 2013

43

Evaluation of 5-year imatinib treatment of 458 patients with CP-CML in routine clinical practice and prognostic impact of different BCR-ABL cutoff levels

Klamová, Hana, Poláková, Kateřina Machová, Mužík, Jan, Ráčil, Zdeněk, Žáčková, Daniela, Steinerová, Kateřina, Karas, Michal, Faber, Edgar, Demečková, Eva, Michalovičová-Sninská, Zuzana, Voglová, Jaros

Journal:

Cancer Medicine

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

44

Assessment of adenosine triphosphate-binding cassette subfamily B member 1 ( ABCB1 ) mRNA expression in patients with de novo chronic myelogenous leukemia: the role of different cell types

Racil, Zdenek, Razga, Filip, Polakova, Katerina Machova, Buresova, Lucie, Polivkova, Vaclava, Dvorakova, Dana, Zackova, Daniela, Klamova, Hana, Cetkovsky, Petr, Mayer, Jiri

Journal:

Leukemia and Lymphoma

Year:

2011

Language:

english

File:

PDF, 304 KB

english, 2011

45

Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing

Linhartova, Jana, Hovorkova, Lenka, Soverini, Simona, Benesova, Adela, Jaruskova, Monika, Klamova, Hana, Zuna, Jan, Machova Polakova, Katerina

Journal:

Molecular Cancer

Year:

2015

Language:

english

File:

PDF, 1.82 MB

english, 2015

46

Unusually Long Survival of a 67-Year-Old Patient with Near-Tetraploid Acute Myeloid Leukemia M0 without Erythroblastic and Megakaryocytic Dysplasia

Lemež, Petr, Klamová, Hana, Zemanová, Zuzana, Marinov, Iuri, Fuchs, Ota, Schwarz, Jiří, Březinová, Jana, Provazníková, Dana, Kostečka, Arnošt, Marková, Jana, Michalová, Kyra, Jelínek, Jaroslav

Journal:

Acta Haematologica

Year:

2011

Language:

english

File:

PDF, 176 KB

english, 2011

47

Changes of Immunological Profiles in Patients with Chronic Myeloid Leukemia in the Course of Treatment

Humlová, Zuzana, Klamová, Hana, Janatková, Ivana, Malíčková, Karin, Králíková, Petra, Šterzl, Ivan, Roth, Zdeněk, Hamšíková, Eva, Vonka, Vladimír

Journal:

Clinical & Developmental Immunology

Year:

2010

Language:

english

File:

PDF, 126 KB

english, 2010

48

Bmi-1 over-expression plays a secondary role in chronic myeloid leukemia transformation

Merkerova, Michaela, Bruchova, Hana, Kracmarova, Alzbeta, Klamova, Hana, Brdicka, Radim

Journal:

Leukemia and Lymphoma

Year:

2007

Language:

english

File:

PDF, 465 KB

english, 2007

49

Kynurenine and uric acid levels in chronic myeloid leukemia patients

Vonka, Vladimir, Humlova, Zuzana, Klamova, Hana, Kujovska-Krcmova, Lenka, Petrackova, Martina, Hamsikova, Eva, Krmencikova-Fliegl, Monika, Duskova, Martina, Roth, Zdenek

Journal:

Year:

2015

Language:

english

File:

PDF, 207 KB

english, 2015

50

Perinucleolar heterochromatin during the cell differentiation using human leukemic neutrophils as a convenient model

Smetana, Karel, Klamová, Hana, Jirásková, Ilona, Mikulenková, Dana

Journal:

Journal of Applied Biomedicine

Year:

2015

Language:

english

File:

PDF, 1.38 MB

english, 2015